Limited CDC study finds Delta Wave did not change hospitalization outcomes

Scientists from the Centers for Disease Control and Prevention on Friday looked into whether the Delta variant of the coronavirus causes...


Scientists from the Centers for Disease Control and Prevention on Friday looked into whether the Delta variant of the coronavirus causes more serious illness, finding no significant differences during the illnesses of hospital patients during the Delta wave compared to the start of the pandemic.

But larger, more detailed studies from a number of other countries have found that people with Delta infections were significantly more likely to be hospitalized in the first place – a trend the CDC study did. could not address due to the limitations of its data. The CDC study also said the proportion of older hospitalized patients requiring intensive care or dying showed signs of increasing during the Delta Wave.

Delta’s higher infectivity level made it a far greater challenge than earlier versions of the virus, but the question of whether it also causes more serious illness has arisen as it swept the world. The Alpha variant, an earlier version first detected in Britain, appeared to be linked to a higher risk of death, although scientists also tried to understand if factors other than the variant played a role.

Studies in England, Scotland, Canada and Singapore suggested that the Delta variant was associated with more serious illness, a finding that scientists say increases the risk that outbreaks of the variant in unvaccinated areas put more strain on health systems. Unlike the CDC study, these studies relied on genomic sequencing, allowing researchers to distinguish Delta variant infections and follow patients before they entered a hospital.

Without access to the sequencing data, CDC researchers could not determine which variants the patients might have been infected with. He also looked at patients already admitted to hospitals, making it impossible to determine whether they were at a higher risk of needing hospital care in the first place.

The study, published Friday, looked at around 7,600 Covid hospitalizations, comparing July and August – when Delta was dominant – to months prior to this year, and found no significant changes in inpatient outcomes.

The study said that the proportion of hospitalized patients aged 50 and over who died or admitted to intensive care “generally tended to increase over the Delta period”, although the differences were not statistically significant and there was research. additional are needed. In the hospitals included in the study, around 70% of Covid patients were not vaccinated.

The researchers said the results matched those of other CDC Studies using similar methods that showed no significant difference in outcomes for young people hospitalized before and during the Delta flare.

Outside scientists questioned the reliability of the study.

Dr. David Fisman, epidemiologist at the University of Toronto, conducted a larger study which found that people infected with the Delta variant were about twice as likely to be hospitalized as people infected with variants that were not considered to be of concern. He said these scans should monitor the range of factors that affect the disease course of Covid patients, and the availability of vaccines, tests and treatments all changed during the pandemic.

“Since this is the USCDC, I am really surprised at the small sample sizes for people with more detailed clinical information, as well as the use of such rudimentary statistical methods to process this data,” said he declared.

Dr. Fisman’s study, based on 200,000 cases and published this month, also showed a significant increase in the risk of ICU admission and death in people infected with the Delta variant, after taking take into account their age, gender, vaccination status and other factors.

About 70 percent of people with Delta infections in the study were unvaccinated and 28 percent were partially vaccinated. Fully vaccinated people are highly protected against Covid.

Likewise, a study in Scotland as of June, based on 20,000 Covid cases, showed Delta infections to be associated with an 85% higher risk of hospitalization, although this allows a large degree of uncertainty as to the precise figure.

And data from England, taken from 43,000 cases and published in August, found that people infected with the Delta variant were just over twice as likely to be hospitalized as people with the Alpha variant, although the researchers of this study were not sure of the exact figure either.

About three-quarters of the patients in this study were unvaccinated and most of the rest were only partially vaccinated.

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Newsrust - US Top News: Limited CDC study finds Delta Wave did not change hospitalization outcomes
Limited CDC study finds Delta Wave did not change hospitalization outcomes
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