Most people don't need a Covid vaccine booster, new review finds

None of the coronavirus vaccine data to date provides credible evidence to support boosters for the general population, according to a ...

None of the coronavirus vaccine data to date provides credible evidence to support boosters for the general population, according to a notice published Monday by an international group of scientists, including some from the Food and Drug Administration and the World Health Organization.

The 18 authors include Dr Philip Krause and Dr Marion Gruber, FDA scientists who announced last month that they would be leaving the agency, at least in part because they disagreed with the Biden administration’s push for boosters before federal scientists could review the evidence and make recommendations.

Biden administration offered to give boosters eight months later the first shots. But many scientists have opposed to the plan, claiming that vaccines continue to be potent against serious illness and hospitalization. An FDA advisory committee is planned to meet Friday to review the data.

In the new review, published in The Lancet, experts said that whatever benefit boosters provide, it won’t outweigh the benefit of using these doses to protect the billions of people who are still not vaccinated in the world. Boosters may be helpful in some people with weakened immune systems, they said, but are not yet necessary for the general population.

Several studies published by the Centers for Disease Control and Prevention, including three on Fridaysuggest that although efficacy against Delta variant infection appears to decline slightly over time, vaccines remain stable against serious illness in all age groups. It is only in people over the age of 75 that vaccines show some weakening of protection against hospitalization.

The immunity conferred by vaccines relies on protection against both antibodies and immune cells. Although antibody levels may decline over time – and increase the risk of infection – the body’s memory for the virus is long lasting.

The vaccines are slightly less effective against infection with the Delta variant than with the Alpha variant, but the virus has not yet evolved to evade sustained responses from immune cells, experts said. Boosters may possibly be needed even for the general population if a variant emerges that bypasses the immune response.

Experts have warned that promoting booster shots before they’re needed, as well as any reports of side effects from booster shots, such as heart problems or Guillain-BarrĂ© syndrome, could undermine confidence in the primary series. .

Data from Israel suggests that booster doses improve protection against infection. But that evidence was gathered about a week after the third dose and may not hold up over time, experts said.

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Newsrust - US Top News: Most people don't need a Covid vaccine booster, new review finds
Most people don't need a Covid vaccine booster, new review finds
Newsrust - US Top News
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