CDC Expert Panel Meets To Determine Who Gets Booster Injections After FDA Decision

Scientific advisers from the Centers for Disease Control and Prevention will face a thorny challenge on Thursday: who qualifies for the ...

Scientific advisers from the Centers for Disease Control and Prevention will face a thorny challenge on Thursday: who qualifies for the new Pfizer-BioNTech coronavirus booster and why?

Wednesday evening, the Food and Drug Administration authorized booster shots for people over 65 who received their second at least six months earlier. The agency has also authorized recalls for adult Pfizer-BioNTech beneficiaries who are at high risk of severe Covid-19, or who are at risk of serious complications due to exposure to the virus in their work.

About 22 million Americans have at least six months past their second dose of Pfizer, according to the CDC. About half are 65 years of age or older.

But who exactly is at risk of getting seriously ill? What does it mean to be exposed at work? Are teachers seen as exposed or as frontline health workers? And what about the Americans who got the Moderna and Johnson & Johnson shots?

These are questions scientists at the CDC’s Advisory Committee on Immunization Practices will debate on Thursday, and their decisions will shape the direction of the federal government. The committee’s recommendations are not binding, and state officials sometimes implement their own criteria. Yet its decisions are likely to influence who receives the booster injections in practice.

In its deliberations on Wednesday, the CDC’s advisory committee focused on the unanswered questions.

A third dose undoubtedly increases antibody levels, the experts concluded. But it is not known so far how long this increase lasts, if it translates into significant additional protection against serious illnesses and if it can significantly reduce the transmission of the virus.

Scientists on the committee also noted the lack of data on safety, especially among young people. And several advisers said they believe the goal of the reminders should be to prevent serious illness, hospitalizations and death, rather than to prevent infection.

“I don’t think there is any hope that vaccines like the ones we have will prevent infection after the first, maybe, few weeks that you have these extraordinary immediate responses,” said Dr Sarah. Long, pediatric infectious disease expert at Drexel. Philadelphia University College of Medicine.

The advisers also looked at the practicalities of approving a vaccine booster from Pfizer, but not Moderna or Johnson & Johnson. Recipients of these vaccines may hear that boosters are needed, but they cannot yet receive them.

“It’s a big public health panic that we would like to avoid,” said Dr Long.

Moderna sought FDA clearance for the booster shots, but at half the dose given in the first two.

Mixing the first shots of the Moderna vaccine with a Pfizer booster – or vice versa – is untested ground, and federal agencies are still reluctant to take action that the evidence does not explicitly support.

Some global health experts have criticized the Biden administration for pushing the booster shots when much of the world has yet to receive a first dose. But on Wednesday, Jen Psaki, the White House press secretary, argued that it was a “false choice”.

On Wednesday morning, President Biden said the United States would purchase an additional 500 million doses of the Pfizer-BioNTech vaccine to be donated worldwide, doubling a purchase in July.

“We now give the world three hits for every hit we put in an American’s arm, and our view continues to be that we can do both,” Ms. Psaki said. “Our view also continues to be that frankly the rest of the world needs to step up and do more.”

Sharon LaFraniere and Noah Weiland contributed to Washington reporting. Daniel E. Slotnik contributed to New York reporting.

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Newsrust - US Top News: CDC Expert Panel Meets To Determine Who Gets Booster Injections After FDA Decision
CDC Expert Panel Meets To Determine Who Gets Booster Injections After FDA Decision
Newsrust - US Top News
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