What to know about boosters if you have the Johnson & Johnson vaccine

Without strong data on the long-term effectiveness of the Johnson & Johnson vaccine, it is difficult for health officials to recommen...

Without strong data on the long-term effectiveness of the Johnson & Johnson vaccine, it is difficult for health officials to recommend boosters, said John Moore, virologist at Weill Cornell Medicine. “If you are making data-driven decisions and you don’t have the data, what can you do? ” he said. “It’s sort of the dilemma. Public confidence in vaccines usually depends on seeing how sausage is made, seeing that it is a transparent and data driven process. “

Clinical trials, conducted before the Delta variant became widespread, found that the Johnson & Johnson vaccine had 72 percent efficiency overall in the United States, lower than the about 95 percent efficiency Pfizer and Moderna vaccines. However, it is difficult to make direct comparisons between vaccines, which have been tested in different places and at different times.

All of the available vaccines appear to be losing some efficacy against Delta, which may be able to evade some of the immune system’s antibodies. The Johnson & Johnson vaccine is no exception. “You would expect there to be some degree of resistance against Delta, because there always is,” Dr. Moore said.

Small laboratory studies have given conflicting results on the protection of the Johnson & Johnson vaccine against Delta. Last month, Johnson & Johnson said that a single dose of his vaccine elicited a strong immune response against Delta and the response lasted for at least eight months.

But the data from another recent laboratory study suggested that a single dose of the vaccine elicited a relatively weak antibody response against Delta, which may make boosters more essential.

The first real data on the vaccine’s effectiveness against the variant were released this month. The data, which are preliminary results from clinical trials with nearly 500,000 healthcare workers in South Africa, suggests that a single dose of the vaccine had efficiency up to 96 percent against death and 71% against hospitalizations due to infections caused by Delta.

It was “a very large analysis and very clear results showing that the J. & J. vaccine provided substantial protection against the Delta variant, ”said Dr. Dan Barouch, a virologist at Beth Israel Deaconess Medical Center in Boston who conducted studies for Johnson & Johnson but was not involved in the trial in South Africa. South.

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Newsrust - US Top News: What to know about boosters if you have the Johnson & Johnson vaccine
What to know about boosters if you have the Johnson & Johnson vaccine
Newsrust - US Top News
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